Critical Care Infusion Calculator (mcg/kg/min ↔ mL/hr)
Calculates infusion pump rate (mL/hr) for vasopressors/inotropes ordered in mcg/kg/min.
⚠️ Educational Calculation & Clinical Safety Safeguard: HIGH-ALERT MEDICATION: Vasopressor infusions require dedicated line/lumen, continuous haemodynamic monitoring, and independent double-check. Educational calculations do not replace clinician assessment, patient-specific laboratory monitoring, or institutional prescribing protocols.
Interactive Calculator
Allowed physiological/compounding range: 0.01 to 100 mcg/kg/min
Allowed physiological/compounding range: 1 to 250 kg
Allowed physiological/compounding range: 0.1 to 5000 mg
Allowed physiological/compounding range: 1 to 1000 mL
Calculated Output (mL/hr (and mcg/mL))
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Step-by-Step Mathematical Derivation & Explanation:
Validated Formula & Conversion Rules
Concentration (mcg/mL) = [Drug (mg) × 1000] / Volume (mL); Rate (mL/hr) = [Dose (mcg/kg/min) × Weight (kg) × 60] / Concentration (mcg/mL)Worked Clinical Example
Dopamine 5 mcg/kg/min for a 70 kg patient using 200 mg in 250 mL (800 mcg/mL): Rate = (5 × 70 × 60) / 800 = 21000 / 800 = 26.25 mL/hr.
Rounding Rules, Assumptions & Source References
- Rounding Rule: Program smart syringe/infusion pumps to 0.1 mL/hr precision.
- Clinical Assumptions & Limitations: Validated only within the stated physiological input boundaries. For paediatric, renal (Cockcroft-Gault), and critical-care infusion calculations, always cross-check against official product labelling and institutional guidelines.
- Source References: Indian Pharmacopoeia (IP 2022), National Formulary of India (NFI), British National Formulary (BNF), and NCBI Bookshelf Clinical Pharmacology Compendia.